Prevention
Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population
Batzella E, Gutierrez de Rubalcava Doblas J, Porcu G, Bressan S, Barbieri E, Giaquinto C, Cantarutti A, Canova C.
Sci Rep. 2025 Jan 28;15(1):3525. doi: 10.1038/s41598-025-87997-3.
PMID: 39875635
SARS-CoV-2
Incidence of severe and non-severe SARS-CoV-2 infections in children and adolescents: a population-based cohort study using six healthcare databases from Italy, Spain, and Norway
Durán CE, Riefolo F, Gini R, Barbieri E, Messina D, Garcia P, Martin M, Villalobos F, Stona L, Carreras JJ, Urchueguía A, Correcher-Martínez E, Zhao J, Lupattelli A, Nordeng H, Sturkenboom M.
Eur J Pediatr. 2024 Nov 13;184(1):6. doi: 10.1007/s00431-024-05864-1.
PMID: 39535547
ACUTE RESPIRATORY TRACT INFECTIONS
A silent strain: the unseen burden of acute respiratory infections in children
Boracchini R, Canova B, Ferrara P, Cantarutti L, Giaquinto C, Di Chiara C, Cantarutti A.
Ital J Pediatr. 2024 Sep 7;50(1):167. doi: 10.1186/s13052-024-01754-2.
PMID: 39244583
SARS-CoV-2
Drug utilisation in children and adolescents before and after the start of the COVID-19 pandemic: Interrupted time-series analyses in three European countries
Pedersen E, Tripodi E, Aakjær M, Li H, Cantarutti A, Nyberg F, Andersen M, Lupattelli A, Nordeng H.Paediatr Perinat Epidemiol. 2024 Aug;38(6):450-460. doi: 10.1111/ppe.13046. Epub 2024 Feb 1.
PMID: 38299727
Antibiotic treatment
Association Between Early-Life Exposure to Antibiotics and Development of Child Obesity: Population-Based Study in Italy
Cantarutti A, Rescigno P, Da Borso C, Gutierrez de Rubalcava Doblas J, Bressan S, Barbieri E, Giaquinto C, Canova C.
JMIR Public Health Surveill. 2024 May 31;10:e51734. doi: 10.2196/51734.
PMID: 38820573
ACUTE RESPIRATORY TRACT INFECTIONS
Monitoring the Epidemiology of Otitis Using Free-Text Pediatric Medical Notes: A Deep Learning Approach
Lanera C, Lorenzoni G, Barbieri E, Piras G, Magge A, Weissenbacher D, Donà D, Cantarutti L, Gonzalez-Hernandez G, Giaquinto C, Gregori D.
J Pers Med. 2023 Dec 25;14(1):28. doi: 10.3390/jpm14010028.
PMID: 38248729
SARS-CoV-2
Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19
Di Chiara C, Barbieri E, Chen YX, Visonà E, Cavagnis S, Sturniolo G, Parca A, Liberati C, Cantarutti L, Lupattelli A, Le Prevost M, Corrao G, Giaquinto C, Donà D, Cantarutti A.
Acta Paediatr. 2023 Dec;112(12):2563-2571. doi: 10.1111/apa.16966. Epub 2023 Sep 9.
PMID: 37688774
ACUTE RESPIRATORY TRACT INFECTIONS
Assessing the burden of bronchiolitis and lower respiratory tract infections in children ≤24 months of age in Italy, 2012-2019
Barbieri E, Cavagnis S, Scamarcia A, Cantarutti L, Bertizzolo L, Bangert M, Parisi S, Cantarutti A, Baraldi E, Giaquinto C, Baldo V.
Front Pediatr. 2023 May 5;11:1143735. doi: 10.3389/fped.2023.1143735. eCollection 2023.
PMID: 37215598
Antibiotic treatment, Dermatological disorders
Retrospective Analysis of the Real-World Use of Topical Antimicrobials in the Paediatric Population with Impetigo in Italy: Focus on the Role of Ozenoxacin 1% Cream
Barbieri E, Cavagnis S, Boracchini R, Scamarcia A, Testa A, Ciarniello MG, Martinelli B, Cantarutti L, Giaquinto C, Cantarutti A. Children (Basel). 2023 Mar 13;10(3):547. doi: 10.3390/children10030547.
PMID: 36980105
SARS-CoV-2
The Association Between Pediatric COVID-19 Vaccination and Socioeconomic Position: Nested Case-Control Study From the Pedianet Veneto Cohort
Batzella E, Cantarutti A, Caranci N, Giaquinto C, Barbiellini Amidei C, Canova C. JMIR Public Health Surveill.
2023 Feb 1;9:e44234. doi: 10.2196/44234.
PMID: 36645419
ACUTE RESPIRATORY TRACT INFECTIONS
The Economic Burden of Pneumococcal Disease in Children: A Population-Based Investigation in the Veneto Region of Italy
Barbieri E, Porcu G, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 Sep 3;9(9):1347. doi: 10.3390/children9091347.
PMID: 36138656
Antibiotic treatment, Dermatological disorders
Early-life exposure to antibiotics and subsequent development of atopic dermatitis
Cantarutti A, Amidei CB, Bonaugurio AS, Rescigno P, Canova C.
Expert Rev Clin Pharmacol. 2022 Jun;15(6):779-785. doi: 10.1080/17512433.2022.2092471. Epub 2022 Jun 21.
PMID: 35723891
Machine learning
A Deep Learning Approach to Estimate the Incidence of Infectious Disease Cases for Routinely Collected Ambulatory Records: The Example of Varicella-Zoster
Lanera C, Baldi I, Francavilla A, Barbieri E, Tramontan L, Scamarcia A, Cantarutti L, Giaquinto C, Gregori D.
Int J Environ Res Public Health. 2022 May 13;19(10):5959. doi: 10.3390/ijerph19105959.
PMID: 35627495
ACUTE RESPIRATORY TRACT INFECTIONS
A Retrospective Analysis to Estimate the Burden of Invasive Pneumococcal Disease and Non-Invasive Pneumonia in Children <15 Years of Age in the Veneto Region, Italy
Barbieri E, Porcu G, Hu T, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 May 3;9(5):657. doi: 10.3390/children9050657.
PMID: 35626834
Dermatological disorders
Non-bullous Impetigo: Incidence, Prevalence, and Treatment in the Pediatric Primary Care Setting in Italy
Barbieri E, Porcu G, Dona’ D, Falsetto N, Biava M, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Front Pediatr. 2022 Mar 31;10:753694. doi: 10.3389/fped.2022.753694. eCollection 2022.
PMID: 35433549
Antibiotic treatment
Antibiotic Prescription Patterns in the Paediatric Primary Care Setting before and after the COVID-19 Pandemic in Italy: An Analysis Using the AWaRe Metrics
Barbieri E, Liberati C, Cantarutti A, Di Chiara C, Lupattelli A, Sharland M, Giaquinto C, Hsia Y, Doná D.
Antibiotics (Basel). 2022 Mar 29;11(4):457. doi: 10.3390/antibiotics11040457.
PMID: 35453209
ACUTE RESPIRATORY TRACT INFECTIONS
A Retrospective Database Analysis to Estimate the Burden of Acute Otitis Media in Children Aged <15 Years in the Veneto Region (Italy)
Barbieri E, Porcu G, Hu T, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 Mar 19;9(3):436. doi: 10.3390/children9030436.
PMID: 35327808
Antibiotic treatment
Antibiotic Prescribing Patterns in Paediatric Primary Care in Italy: Findings from 2012-2018
Barbieri E, di Chiara C, Costenaro P, Cantarutti A, Giaquinto C, Hsia Y, Doná D.
Antibiotics (Basel). 2021 Dec 24;11(1):18. doi: 10.3390/antibiotics11010018.
PMID: 35052895
Prevention
Use of the Bacterial Lysate OM-85 in the Paediatric Population in Italy: A Retrospective Cohort Study
Cantarutti A, Barbieri E, Scamarcia A, Cantarutti L, Canova C, Giaquinto C.
Int J Environ Res Public Health. 2021 Jun 26;18(13):6871. doi: 10.3390/ijerph18136871.
PMID: 34206831
Other
Incidence Rates of Autoimmune Diseases in European Healthcare Databases: A Contribution of the ADVANCE Project
Willame C, Dodd C, van der Aa L, Picelli G, Emborg HD, Kahlert J, Gini R, Huerta C, Martín-Merino E, McGee C, de Lusignan S, Roberto G, Villa M, Weibel D, Titievsky L, Sturkenboom MCJM.
Drug Saf. 2021 Mar;44(3):383-395. doi: 10.1007/s40264-020-01031-1. Epub 2021 Jan 19.
PMID: 33462778
ACUTE RESPIRATORY TRACT INFECTIONS
Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
Barbieri E, Cantarutti A, Cavagnis S, Cantarutti L, Baraldi E, Giaquinto C, Donà D.
NPJ Prim Care Respir Med. 2021 Mar 19;31(1):15. doi: 10.1038/s41533-021-00228-w.
PMID: 33741991
ACUTE RESPIRATORY TRACT INFECTIONS, Antibiotic treatment
Antibiotic Prescriptions for Children With Community-acquired Pneumonia: Findings From Italy
Costenaro P, Cantarutti A, Barbieri E, Scamarcia A, Oletto A, Sacerdoti P, Lundin R, Cantarutti L, Giaquinto C, Donà D.
Pediatr Infect Dis J. 2021 Feb 1;40(2):130-136. doi: 10.1097/INF.0000000000002934.
PMID: 33055500
Other
ADVANCE system testing: Can safety studies be conducted using electronic healthcare data? An example using pertussis vaccination
Weibel D, Dodd C, Mahaux O, Haguinet F, De Smedt T, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Martín-Merino E, Huerta-Alvarez C, Berencsi K, Emborg HD, Bollaerts K, Bauchau V, Titievsky L, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B38-B46. doi: 10.1016/j.vaccine.2019.06.040. Epub 2019 Oct 31.
PMID: 31677946
Other
ADVANCE system testing: Benefit-risk analysis of a marketed vaccine using multi-criteria decision analysis and individual-level state transition modelling
Bollaerts K, Ledent E, de Smedt T, Weibel D, Emborg HD, Danieli G, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Picelli G, Tramontan L, Sturkenboom M, Bauchau V.
Vaccine. 2020 Dec 22;38 Suppl 2:B65-B75. doi: 10.1016/j.vaccine.2019.09.034. Epub 2019 Oct 31.
PMID: 31677947
Other
Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project
Gini R, Dodd CN, Bollaerts K, Bartolini C, Roberto G, Huerta-Alvarez C, Martín-Merino E, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Becker BFH, Switzer C, Gandhi-Banga S, Bauwens J, van der Maas NAT, Spiteri G, Sdona E, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B56-B64. doi: 10.1016/j.vaccine.2019.07.045. Epub 2019 Oct 31.
PMID: 31677950
Prevention
Preventing recurrent acute otitis media with Streptococcus salivarius 24SMB and Streptococcus oralis 89a five months intermittent treatment: An observational prospective cohort study
Cantarutti A, Rea F, Donà D, Cantarutti L, Passarella A, Scamarcia A, Lundin R, Damiani V, Giaquinto C, Corrao G.
Int J Pediatr Otorhinolaryngol. 2020 May;132:109921. doi: 10.1016/j.ijporl.2020.109921. Epub 2020 Feb 5.
PMID: 32062496
Machine learning
Use of Machine Learning Techniques for Case-Detection of Varicella Zoster Using Routinely Collected Textual Ambulatory Records: Pilot Observational Study
Lanera C, Berchialla P, Baldi I, Lorenzoni G, Tramontan L, Scamarcia A, Cantarutti L, Giaquinto C, Gregori D.
JMIR Med Inform. 2020 May 5;8(5):e14330. doi: 10.2196/14330.
PMID: 32369038
ACUTE RESPIRATORY TRACT INFECTIONS, Antibiotic treatment
Antibiotic prescriptions in acute otitis media and pharyngitis in Italian pediatric outpatients
Barbieri E, Donà D, Cantarutti A, Lundin R, Scamarcia A, Corrao G, Cantarutti L, Giaquinto C.
Ital J Pediatr. 2019 Aug 17;45(1):103. doi: 10.1186/s13052-019-0696-9.
PMID: 31420054
Prevention
Galacto-Oligosaccharide/Polidextrose Enriched Formula Protects against Respiratory Infections in Infants at High Risk of Atopy: A Randomized Clinical Trial
Ranucci G, Buccigrossi V, Borgia E, Piacentini D, Visentin F, Cantarutti L, Baiardi P, Felisi M, Spagnuolo MI, Zanconato S, Baraldi E, Giaquinto C, Guarino A.
Nutrients. 2018 Mar 1;10(3):286. doi: 10.3390/nu10030286.
PMID: 29494489
Antibiotic treatment
Antibiotic Use in Children – A Cross-National Analysis of 6 Countries
Youngster I, Avorn J, Belleudi V, Cantarutti A, Díez-Domingo J, Kirchmayer U, Park BJ, Peiró S, Sanfélix-Gimeno G, Schröder H, Schüssel K, Shin JY, Shin SM, Simonsen GS, Blix HS, Tong A, Trifirò G, Ziv-Baran T, Kim SC.
J Pediatr. 2017 Mar;182:239-244.e1. doi: 10.1016/j.jpeds.2016.11.027. Epub 2016 Dec 21.
PMID: 28012694
Antibiotic treatment
Using Prescription Patterns in Primary Care to Derive New Quality Indicators for Childhood Community Antibiotic Prescribing. de Bie S, Kaguelidou F, Verhamme KM, De Ridder M, Picelli G, Straus SM, Giaquinto C, Stricker BH, Bielicki J, Sharland M, Sturkenboom MC; ARPEC study
Pediatr Infect Dis J. 2016 Dec;35(12):1317-1323. doi: 10.1097/INF.0000000000001324.
PMID: 27626915
Dermatological disorders
Epidemiology of Frequently Occurring Skin Diseases in Italian Children from 2006 to 2012: A Retrospective, Population-Based Study
Cantarutti A, Donà D, Visentin F, Borgia E, Scamarcia A, Cantarutti L, Peruzzi E, Egan CG, Villa M, Giaquinto C; Pedianet.
Pediatr Dermatol. 2015 Sep-Oct;32(5):668-78. doi: 10.1111/pde.12568. Epub 2015 Apr 16.
PMID: 25879514
ACUTE RESPIRATORY TRACT INFECTIONS
Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices
Liese JG, Silfverdal SA, Giaquinto C, Carmona A, Larcombe JH, Garcia-Sicilia J, Fuat A, Garces-Sanchez M, Basanta ML, Hiraldo EM, Cantarutti L, Kroeniger W, Vollmar J, Holl K, Pirçon JY, Rosenlund MR.
Epidemiol Infect. 2014 Aug;142(8):1778-88. doi: 10.1017/S0950268813002744. Epub 2013 Dec 13.
PMID: 24330917
Other
Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and which study designs do we need to assess safety issues?
Valkhoff VE, Schade R, ‘t Jong GW, Romio S, Schuemie MJ, Arfe A, Garbe E, Herings R, Lucchi S, Picelli G, Schink T, Straatman H, Villa M, Kuipers EJ, Sturkenboom MC; Safety of Non-steroidal Anti-inflammatory Drugs (SOS) project.
BMC Pediatr. 2013 Nov 19;13:192. doi: 10.1186/1471-2431-13-192.
PMID: 24252465
Other
Replication of the OMOP experiment in Europe: evaluating methods for risk identification in electronic health record databases
Schuemie MJ, Gini R, Coloma PM, Straatman H, Herings RM, Pedersen L, Innocenti F, Mazzaglia G, Picelli G, van der Lei J, Sturkenboom MC.
Drug Saf. 2013 Oct;36 Suppl 1:S159-69. doi: 10.1007/s40264-013-0109-8.
PMID: 24166232
ACUTE RESPIRATORY TRACT INFECTIONS
Burden of acute otitis media in primary care pediatrics in Italy: a secondary data analysis from the Pedianet database
Marchisio P, Cantarutti L, Sturkenboom M, Girotto S, Picelli G, Dona D, Scamarcia A, Villa M, Giaquinto C; Pedianet.
BMC Pediatr. 2012 Nov 29;12:185. doi: 10.1186/1471-2431-12-185.
PMID: 23190626
Other
The prescribing of analgesics and non-steroidal anti-inflammatory drugs in paediatric primary care in the UK, Italy and the Netherlands
Neubert A, Verhamme K, Murray ML, Picelli G, Hsia Y, Sen FE, Giaquinto C, Ceci A, Sturkenboom M, Wong IC; TEDDY Network of Excellence.
Pharmacol Res. 2010 Sep;62(3):243-8. doi: 10.1016/j.phrs.2010.04.006. Epub 2010 May 6.
PMID: 20451614
Other
Comparison of antiepileptic drug prescribing in children in three European countries
Hsia Y, Neubert A, Sturkenboom MC, Murray ML, Verhamme KM, Sen F, Giaquinto C, Ceci A, Wong IC; TEDDY Network of Excellence.
Epilepsia. 2010 May;51(5):789-96. doi: 10.1111/j.1528-1167.2009.02331.x. Epub 2009 Oct 8.
PMID: 19817815
Other
In-label and off-label use of respiratory drugs in the Italian paediatric population
Baiardi P, Ceci A, Felisi M, Cantarutti L, Girotto S, Sturkenboom M, Baraldi E.
Acta Paediatr. 2010 Apr;99(4):544-9. doi: 10.1111/j.1651-2227.2009.01668.x. Epub 2010 Jan 27.
PMID: 20105140
Other
Drug use in children: cohort study in three European countries
Sturkenboom MC, Verhamme KM, Nicolosi A, Murray ML, Neubert A, Caudri D, Picelli G, Sen EF, Giaquinto C, Cantarutti L, Baiardi P, Felisi MG, Ceci A, Wong IC; TEDDY European Network of Excellence.
BMJ. 2008 Nov 24;337:a2245. doi: 10.1136/bmj.a2245.
PMID: 19029175
Dermatological disorders
Incidence of mucocutaneous reactions in children treated with niflumic acid, other nonsteroidal antiinflammatory drugs, or nonopioid analgesics
Sturkenboom M, Nicolosi A, Cantarutti L, Mannino S, Picelli G, Scamarcia A, Giaquinto C; NSAIDs Paediatric Research Group.
Pediatrics. 2005 Jul;116(1):e26-33. doi: 10.1542/peds.2004-0040. Epub 2005 Jun 1.
PMID: 15930187
Other
[Epidemiology and outcomes of varicella in Italy: results of a prospective study of children (0-14 years old) followed up by pediatricians (Pedianet study)]
Giaquinto C, Sturkenboom M, Mannino S, Arpinelli F, Nicolosi A, Cantarutti L; Gruppo di studio sulla varicella in età pediatrica (Pedianet Varicella Study Group).
Ann Ig. 2002 Jul-Aug;14(4 Suppl 6):21-7.
PMID: 12389301 Italian. No abstract available.
Other
Active monitoring of adverse drug reactions in children. Italian Paediatric Pharmacosurveillance Multicenter Group
Menniti-Ippolito G, Raschetti R, Da Cas R, Giaquinto C, Cantarutti L.Lancet. 2000 May 6;355(9215):1613-4. doi: 10.1016/s0140-6736(00)02219-4.
PMID: 10821367