Prevention
Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population
Batzella E, Gutierrez de Rubalcava Doblas J, Porcu G, Bressan S, Barbieri E, Giaquinto C, Cantarutti A, Canova C.
Sci Rep. 2025 Jan 28;15(1):3525. doi: 10.1038/s41598-025-87997-3.
PMID: 39875635
Vaccination
A population database analysis to estimate the varicella vaccine effectiveness in children < 14 years in a high vaccination coverage area from 2004 to 2022
Barbieri E, Cocchio S, Furlan P, Scamarcia A, Cantarutti L, Dona’ D, Giaquinto C, Baldo V.
Vaccine. 2024 Dec 2;42(26):126387. doi: 10.1016/j.vaccine.2024.126387. Epub 2024 Sep 26.
PMID: 39332238
SARS-CoV-2
Incidence of severe and non-severe SARS-CoV-2 infections in children and adolescents: a population-based cohort study using six healthcare databases from Italy, Spain, and Norway
Durán CE, Riefolo F, Gini R, Barbieri E, Messina D, Garcia P, Martin M, Villalobos F, Stona L, Carreras JJ, Urchueguía A, Correcher-Martínez E, Zhao J, Lupattelli A, Nordeng H, Sturkenboom M.
Eur J Pediatr. 2024 Nov 13;184(1):6. doi: 10.1007/s00431-024-05864-1.
PMID: 39535547
ACUTE RESPIRATORY TRACT INFECTIONS
A silent strain: the unseen burden of acute respiratory infections in children
Boracchini R, Canova B, Ferrara P, Cantarutti L, Giaquinto C, Di Chiara C, Cantarutti A.
Ital J Pediatr. 2024 Sep 7;50(1):167. doi: 10.1186/s13052-024-01754-2.
PMID: 39244583
SARS-CoV-2
Drug utilisation in children and adolescents before and after the start of the COVID-19 pandemic: Interrupted time-series analyses in three European countries
Pedersen E, Tripodi E, Aakjær M, Li H, Cantarutti A, Nyberg F, Andersen M, Lupattelli A, Nordeng H.Paediatr Perinat Epidemiol. 2024 Aug;38(6):450-460. doi: 10.1111/ppe.13046. Epub 2024 Feb 1.
PMID: 38299727
Antibiotic treatment
Association Between Early-Life Exposure to Antibiotics and Development of Child Obesity: Population-Based Study in Italy
Cantarutti A, Rescigno P, Da Borso C, Gutierrez de Rubalcava Doblas J, Bressan S, Barbieri E, Giaquinto C, Canova C.
JMIR Public Health Surveill. 2024 May 31;10:e51734. doi: 10.2196/51734.
PMID: 38820573
ACUTE RESPIRATORY TRACT INFECTIONS
Monitoring the Epidemiology of Otitis Using Free-Text Pediatric Medical Notes: A Deep Learning Approach
Lanera C, Lorenzoni G, Barbieri E, Piras G, Magge A, Weissenbacher D, Donà D, Cantarutti L, Gonzalez-Hernandez G, Giaquinto C, Gregori D.
J Pers Med. 2023 Dec 25;14(1):28. doi: 10.3390/jpm14010028.
PMID: 38248729
SARS-CoV-2
Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19
Di Chiara C, Barbieri E, Chen YX, Visonà E, Cavagnis S, Sturniolo G, Parca A, Liberati C, Cantarutti L, Lupattelli A, Le Prevost M, Corrao G, Giaquinto C, Donà D, Cantarutti A.
Acta Paediatr. 2023 Dec;112(12):2563-2571. doi: 10.1111/apa.16966. Epub 2023 Sep 9.
PMID: 37688774
ACUTE RESPIRATORY TRACT INFECTIONS
Assessing the burden of bronchiolitis and lower respiratory tract infections in children ≤24 months of age in Italy, 2012-2019
Barbieri E, Cavagnis S, Scamarcia A, Cantarutti L, Bertizzolo L, Bangert M, Parisi S, Cantarutti A, Baraldi E, Giaquinto C, Baldo V.
Front Pediatr. 2023 May 5;11:1143735. doi: 10.3389/fped.2023.1143735. eCollection 2023.
PMID: 37215598
Antibiotic treatment, Dermatological disorders
Retrospective Analysis of the Real-World Use of Topical Antimicrobials in the Paediatric Population with Impetigo in Italy: Focus on the Role of Ozenoxacin 1% Cream
Barbieri E, Cavagnis S, Boracchini R, Scamarcia A, Testa A, Ciarniello MG, Martinelli B, Cantarutti L, Giaquinto C, Cantarutti A. Children (Basel). 2023 Mar 13;10(3):547. doi: 10.3390/children10030547.
PMID: 36980105
SARS-CoV-2
The Association Between Pediatric COVID-19 Vaccination and Socioeconomic Position: Nested Case-Control Study From the Pedianet Veneto Cohort
Batzella E, Cantarutti A, Caranci N, Giaquinto C, Barbiellini Amidei C, Canova C. JMIR Public Health Surveill.
2023 Feb 1;9:e44234. doi: 10.2196/44234.
PMID: 36645419
ACUTE RESPIRATORY TRACT INFECTIONS
The Economic Burden of Pneumococcal Disease in Children: A Population-Based Investigation in the Veneto Region of Italy
Barbieri E, Porcu G, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 Sep 3;9(9):1347. doi: 10.3390/children9091347.
PMID: 36138656
Antibiotic treatment, Dermatological disorders
Early-life exposure to antibiotics and subsequent development of atopic dermatitis
Cantarutti A, Amidei CB, Bonaugurio AS, Rescigno P, Canova C.
Expert Rev Clin Pharmacol. 2022 Jun;15(6):779-785. doi: 10.1080/17512433.2022.2092471. Epub 2022 Jun 21.
PMID: 35723891
Machine learning
A Deep Learning Approach to Estimate the Incidence of Infectious Disease Cases for Routinely Collected Ambulatory Records: The Example of Varicella-Zoster
Lanera C, Baldi I, Francavilla A, Barbieri E, Tramontan L, Scamarcia A, Cantarutti L, Giaquinto C, Gregori D.
Int J Environ Res Public Health. 2022 May 13;19(10):5959. doi: 10.3390/ijerph19105959.
PMID: 35627495
ACUTE RESPIRATORY TRACT INFECTIONS
A Retrospective Analysis to Estimate the Burden of Invasive Pneumococcal Disease and Non-Invasive Pneumonia in Children <15 Years of Age in the Veneto Region, Italy
Barbieri E, Porcu G, Hu T, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 May 3;9(5):657. doi: 10.3390/children9050657.
PMID: 35626834
Antibiotic treatment
Antibiotic Prescription Patterns in the Paediatric Primary Care Setting before and after the COVID-19 Pandemic in Italy: An Analysis Using the AWaRe Metrics
Barbieri E, Liberati C, Cantarutti A, Di Chiara C, Lupattelli A, Sharland M, Giaquinto C, Hsia Y, Doná D.
Antibiotics (Basel). 2022 Mar 29;11(4):457. doi: 10.3390/antibiotics11040457.
PMID: 35453209
ACUTE RESPIRATORY TRACT INFECTIONS
A Retrospective Database Analysis to Estimate the Burden of Acute Otitis Media in Children Aged <15 Years in the Veneto Region (Italy)
Barbieri E, Porcu G, Hu T, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 Mar 19;9(3):436. doi: 10.3390/children9030436.
PMID: 35327808
Antibiotic treatment
Antibiotic Prescribing Patterns in Paediatric Primary Care in Italy: Findings from 2012-2018
Barbieri E, di Chiara C, Costenaro P, Cantarutti A, Giaquinto C, Hsia Y, Doná D.
Antibiotics (Basel). 2021 Dec 24;11(1):18. doi: 10.3390/antibiotics11010018.
PMID: 35052895
Gastrointestinal diseases
Association of Treated and Untreated Gastroesophageal Reflux Disease in the First Year of Life with the Subsequent Development of Asthma
Cantarutti A, Barbiellini Amidei C, Valsecchi C, Scamarcia A, Corrao G, Gregori D, Giaquinto C, Ludvigsson JF, Canova C.
Int J Environ Res Public Health. 2021 Sep 13;18(18):9633. doi: 10.3390/ijerph18189633.
PMID: 34574556
Prevention
Use of the Bacterial Lysate OM-85 in the Paediatric Population in Italy: A Retrospective Cohort Study
Cantarutti A, Barbieri E, Scamarcia A, Cantarutti L, Canova C, Giaquinto C.
Int J Environ Res Public Health. 2021 Jun 26;18(13):6871. doi: 10.3390/ijerph18136871.
PMID: 34206831
ACUTE RESPIRATORY TRACT INFECTIONS
Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
Barbieri E, Cantarutti A, Cavagnis S, Cantarutti L, Baraldi E, Giaquinto C, Donà D.
NPJ Prim Care Respir Med. 2021 Mar 19;31(1):15. doi: 10.1038/s41533-021-00228-w.
PMID: 33741991
ACUTE RESPIRATORY TRACT INFECTIONS, Antibiotic treatment
Antibiotic Prescriptions for Children With Community-acquired Pneumonia: Findings From Italy
Costenaro P, Cantarutti A, Barbieri E, Scamarcia A, Oletto A, Sacerdoti P, Lundin R, Cantarutti L, Giaquinto C, Donà D.
Pediatr Infect Dis J. 2021 Feb 1;40(2):130-136. doi: 10.1097/INF.0000000000002934.
PMID: 33055500
Vaccination
Advance system testing: Vaccine benefit studies using multi-country electronic health data – The example of pertussis vaccination
Tin Tin Htar M, de Ridder M, Braeye T, Correa A, McGee C, de Lusignan S, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Tramontan L, Danieli G, Picelli G, van der Maas N, Berencsi K, Arnheim-Dahlström L, Heininger U, Emborg HD, Weibel D, Bollaerts K, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B31-B37. doi: 10.1016/j.vaccine.2019.08.078. Epub 2019 Oct 31.
PMID: 31677949
Vaccination
ADVANCE system testing: Can coverage of pertussis vaccination be estimated in European countries using electronic healthcare databases: An example
Emborg HD, Kahlert J, Braeye T, Bauwens J, Bollaerts K, Danieli G, Duarte-Salles T, Glismann S, Huerta-Alvarez C, de Lusignan S, Martín-Merino E, McGee C, Correa A, Tramontan L, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B22-B30. doi: 10.1016/j.vaccine.2019.07.039. Epub 2019 Oct 31.
PMID: 31677953
Vaccination
ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations
Sturkenboom M, Braeye T, van der Aa L, Danieli G, Dodd C, Duarte-Salles T, Emborg HD, Gheorghe M, Kahlert J, Gini R, Huerta-Alvarez C, Martín-Merino E, McGee C, de Lusignan S, Picelli G, Roberto G, Tramontan L, Villa M, Weibel D, Titievsky L.
Vaccine. 2020 Dec 22;38 Suppl 2:B8-B21. doi: 10.1016/j.vaccine.2020.01.100. Epub 2020 Feb 12.
PMID: 32061385
Vaccination
ADVANCE system testing: Estimating the incidence of adverse events following pertussis vaccination in healthcare databases with incomplete exposure data
Dodd C, de Ridder M, Weibel D, Mahaux O, Haguinet F, de Smedt T, de Lusignan S, McGee C, Duarte-Salles T, Emborg HD, Huerta-Alvarez C, Martín-Merino E, Picelli G, Berencsi K, Danieli G, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B47-B55. doi: 10.1016/j.vaccine.2020.03.050. Epub 2020 Apr 9.
PMID: 32280043
Prevention
Preventing recurrent acute otitis media with Streptococcus salivarius 24SMB and Streptococcus oralis 89a five months intermittent treatment: An observational prospective cohort study
Cantarutti A, Rea F, Donà D, Cantarutti L, Passarella A, Scamarcia A, Lundin R, Damiani V, Giaquinto C, Corrao G.
Int J Pediatr Otorhinolaryngol. 2020 May;132:109921. doi: 10.1016/j.ijporl.2020.109921. Epub 2020 Feb 5.
PMID: 32062496
Machine learning
Use of Machine Learning Techniques for Case-Detection of Varicella Zoster Using Routinely Collected Textual Ambulatory Records: Pilot Observational Study
Lanera C, Berchialla P, Baldi I, Lorenzoni G, Tramontan L, Scamarcia A, Cantarutti L, Giaquinto C, Gregori D.
JMIR Med Inform. 2020 May 5;8(5):e14330. doi: 10.2196/14330.
PMID: 32369038
Vaccination
Age-specific vaccination coverage estimates for influenza, human papillomavirus and measles containing vaccines from seven population-based healthcare databases from four EU countries – The ADVANCE project
Braeye T, Emborg HD, Llorente-García A, Huerta C, Martín-Merino E, Duarte-Salles T, Danieli G, Tramontan L, Weibel D, McGee C, Villa M, Gini R, Lehtinen M, Titievsky L, Sturkenboom M.
Vaccine. 2020 Apr 3;38(16):3243-3254. doi: 10.1016/j.vaccine.2020.02.082. Epub 2020 Mar 12.
PMID: 32171573
ACUTE RESPIRATORY TRACT INFECTIONS, Antibiotic treatment
Antibiotic prescriptions in acute otitis media and pharyngitis in Italian pediatric outpatients
Barbieri E, Donà D, Cantarutti A, Lundin R, Scamarcia A, Corrao G, Cantarutti L, Giaquinto C.
Ital J Pediatr. 2019 Aug 17;45(1):103. doi: 10.1186/s13052-019-0696-9.
PMID: 31420054
Vaccination
Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy
Giaquinto C, Gabutti G, Baldo V, Villa M, Tramontan L, Raccanello N, Russo F, Poma C, Scamarcia A, Cantarutti L, Lundin R, Perinetti E, Cornen X, Thomas S, Ballandras C, Souverain A, Hartwig S.
BMC Infect Dis. 2018 Mar 5;18(1):103. doi: 10.1186/s12879-018-3017-9.
PMID: 29506477
Prevention
Galacto-Oligosaccharide/Polidextrose Enriched Formula Protects against Respiratory Infections in Infants at High Risk of Atopy: A Randomized Clinical Trial
Ranucci G, Buccigrossi V, Borgia E, Piacentini D, Visentin F, Cantarutti L, Baiardi P, Felisi M, Spagnuolo MI, Zanconato S, Baraldi E, Giaquinto C, Guarino A.
Nutrients. 2018 Mar 1;10(3):286. doi: 10.3390/nu10030286.
PMID: 29494489
Gastrointestinal diseases
Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases
Ferrajolo C, Verhamme KM, Trifirò G, ‘t Jong GW, Picelli G, Giaquinto C, Mazzaglia G, Stricker BH, Rossi F, Capuano A, Sturkenboom MC.
Drug Saf. 2017 Apr;40(4):305-315. doi: 10.1007/s40264-016-0493-y.
PMID: 28025733
Antibiotic treatment
Antibiotic Use in Children – A Cross-National Analysis of 6 Countries
Youngster I, Avorn J, Belleudi V, Cantarutti A, Díez-Domingo J, Kirchmayer U, Park BJ, Peiró S, Sanfélix-Gimeno G, Schröder H, Schüssel K, Shin JY, Shin SM, Simonsen GS, Blix HS, Tong A, Trifirò G, Ziv-Baran T, Kim SC.
J Pediatr. 2017 Mar;182:239-244.e1. doi: 10.1016/j.jpeds.2016.11.027. Epub 2016 Dec 21.
PMID: 28012694
Antibiotic treatment
Using Prescription Patterns in Primary Care to Derive New Quality Indicators for Childhood Community Antibiotic Prescribing. de Bie S, Kaguelidou F, Verhamme KM, De Ridder M, Picelli G, Straus SM, Giaquinto C, Stricker BH, Bielicki J, Sharland M, Sturkenboom MC; ARPEC study
Pediatr Infect Dis J. 2016 Dec;35(12):1317-1323. doi: 10.1097/INF.0000000000001324.
PMID: 27626915
Gastrointestinal diseases
Community-Acquired Rotavirus Gastroenteritis Compared with Adenovirus and Norovirus Gastroenteritis in Italian Children: A Pedianet Study
Donà D, Mozzo E, Scamarcia A, Picelli G, Villa M, Cantarutti L, Giaquinto C.
Int J Pediatr. 2016;2016:5236243. doi: 10.1155/2016/5236243. Epub 2016 Jan 14.
PMID: 26884770
Gastrointestinal diseases
Risk of upper gastrointestinal bleeding from different drug combinations
Masclee GM, Valkhoff VE, Coloma PM, de Ridder M, Romio S, Schuemie MJ, Herings R, Gini R, Mazzaglia G, Picelli G, Scotti L, Pedersen L, Kuipers EJ, van der Lei J, Sturkenboom MC.
Gastroenterology. 2014 Oct;147(4):784-792.e9; quiz e13-4. doi: 10.1053/j.gastro.2014.06.007. Epub 2014 Jun 14.
PMID: 24937265
ACUTE RESPIRATORY TRACT INFECTIONS
Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices
Liese JG, Silfverdal SA, Giaquinto C, Carmona A, Larcombe JH, Garcia-Sicilia J, Fuat A, Garces-Sanchez M, Basanta ML, Hiraldo EM, Cantarutti L, Kroeniger W, Vollmar J, Holl K, Pirçon JY, Rosenlund MR.
Epidemiol Infect. 2014 Aug;142(8):1778-88. doi: 10.1017/S0950268813002744. Epub 2013 Dec 13.
PMID: 24330917
Gastrointestinal diseases
Idiopathic acute liver injury in paediatric outpatients: incidence and signal detection in two European countries
Ferrajolo C, Verhamme KM, Trifirò G, ‘t Jong GW, Giaquinto C, Picelli G, Oteri A, de Bie S, Valkhoff VE, Schuemie MJ, Mazzaglia G, Cricelli C, Rossi F, Capuano A, Sturkenboom MC.
Drug Saf. 2013 Oct;36(10):1007-16. doi: 10.1007/s40264-013-0045-7.
PMID: 23591830
ACUTE RESPIRATORY TRACT INFECTIONS
Burden of acute otitis media in primary care pediatrics in Italy: a secondary data analysis from the Pedianet database
Marchisio P, Cantarutti L, Sturkenboom M, Girotto S, Picelli G, Dona D, Scamarcia A, Villa M, Giaquinto C; Pedianet.
BMC Pediatr. 2012 Nov 29;12:185. doi: 10.1186/1471-2431-12-185.
PMID: 23190626