Prevention

Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population

Batzella E, Gutierrez de Rubalcava Doblas J, Porcu G, Bressan S, Barbieri E, Giaquinto C, Cantarutti A, Canova C.
Sci Rep. 2025 Jan 28;15(1):3525. doi: 10.1038/s41598-025-87997-3.
PMID: 39875635

Vaccination

A population database analysis to estimate the varicella vaccine effectiveness in children < 14 years in a high vaccination coverage area from 2004 to 2022

Barbieri E, Cocchio S, Furlan P, Scamarcia A, Cantarutti L, Dona’ D, Giaquinto C, Baldo V.
Vaccine. 2024 Dec 2;42(26):126387. doi: 10.1016/j.vaccine.2024.126387. Epub 2024 Sep 26.
PMID: 39332238

SARS-CoV-2

Incidence of severe and non-severe SARS-CoV-2 infections in children and adolescents: a population-based cohort study using six healthcare databases from Italy, Spain, and Norway

Durán CE, Riefolo F, Gini R, Barbieri E, Messina D, Garcia P, Martin M, Villalobos F, Stona L, Carreras JJ, Urchueguía A, Correcher-Martínez E, Zhao J, Lupattelli A, Nordeng H, Sturkenboom M.
Eur J Pediatr. 2024 Nov 13;184(1):6. doi: 10.1007/s00431-024-05864-1.
PMID: 39535547

ACUTE RESPIRATORY TRACT INFECTIONS

A silent strain: the unseen burden of acute respiratory infections in children

Boracchini R, Canova B, Ferrara P, Cantarutti L, Giaquinto C, Di Chiara C, Cantarutti A.
Ital J Pediatr. 2024 Sep 7;50(1):167. doi: 10.1186/s13052-024-01754-2.
PMID: 39244583

SARS-CoV-2

Drug utilisation in children and adolescents before and after the start of the COVID-19 pandemic: Interrupted time-series analyses in three European countries

Pedersen E, Tripodi E, Aakjær M, Li H, Cantarutti A, Nyberg F, Andersen M, Lupattelli A, Nordeng H.Paediatr Perinat Epidemiol. 2024 Aug;38(6):450-460. doi: 10.1111/ppe.13046. Epub 2024 Feb 1.
PMID: 38299727

ACUTE RESPIRATORY TRACT INFECTIONS

Monitoring the Epidemiology of Otitis Using Free-Text Pediatric Medical Notes: A Deep Learning Approach

Lanera C, Lorenzoni G, Barbieri E, Piras G, Magge A, Weissenbacher D, Donà D, Cantarutti L, Gonzalez-Hernandez G, Giaquinto C, Gregori D.
J Pers Med. 2023 Dec 25;14(1):28. doi: 10.3390/jpm14010028.
PMID: 38248729

SARS-CoV-2

Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19

Di Chiara C, Barbieri E, Chen YX, Visonà E, Cavagnis S, Sturniolo G, Parca A, Liberati C, Cantarutti L, Lupattelli A, Le Prevost M, Corrao G, Giaquinto C, Donà D, Cantarutti A.
Acta Paediatr. 2023 Dec;112(12):2563-2571. doi: 10.1111/apa.16966. Epub 2023 Sep 9.
PMID: 37688774

ACUTE RESPIRATORY TRACT INFECTIONS

Assessing the burden of bronchiolitis and lower respiratory tract infections in children ≤24 months of age in Italy, 2012-2019

Barbieri E, Cavagnis S, Scamarcia A, Cantarutti L, Bertizzolo L, Bangert M, Parisi S, Cantarutti A, Baraldi E, Giaquinto C, Baldo V.
Front Pediatr. 2023 May 5;11:1143735. doi: 10.3389/fped.2023.1143735. eCollection 2023.
PMID: 37215598

SARS-CoV-2

The Association Between Pediatric COVID-19 Vaccination and Socioeconomic Position: Nested Case-Control Study From the Pedianet Veneto Cohort

Batzella E, Cantarutti A, Caranci N, Giaquinto C, Barbiellini Amidei C, Canova C. JMIR Public Health Surveill.
2023 Feb 1;9:e44234. doi: 10.2196/44234.
PMID: 36645419

ACUTE RESPIRATORY TRACT INFECTIONS

The Economic Burden of Pneumococcal Disease in Children: A Population-Based Investigation in the Veneto Region of Italy

Barbieri E, Porcu G, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 Sep 3;9(9):1347. doi: 10.3390/children9091347.
PMID: 36138656

ACUTE RESPIRATORY TRACT INFECTIONS

A Retrospective Analysis to Estimate the Burden of Invasive Pneumococcal Disease and Non-Invasive Pneumonia in Children <15 Years of Age in the Veneto Region, Italy

Barbieri E, Porcu G, Hu T, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 May 3;9(5):657. doi: 10.3390/children9050657.
PMID: 35626834

ACUTE RESPIRATORY TRACT INFECTIONS

A Retrospective Database Analysis to Estimate the Burden of Acute Otitis Media in Children Aged <15 Years in the Veneto Region (Italy)

Barbieri E, Porcu G, Hu T, Petigara T, Senese F, Prandi GM, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Children (Basel). 2022 Mar 19;9(3):436. doi: 10.3390/children9030436.
PMID: 35327808

Prevention

Use of the Bacterial Lysate OM-85 in the Paediatric Population in Italy: A Retrospective Cohort Study

Cantarutti A, Barbieri E, Scamarcia A, Cantarutti L, Canova C, Giaquinto C.
Int J Environ Res Public Health. 2021 Jun 26;18(13):6871. doi: 10.3390/ijerph18136871.
PMID: 34206831

Other

Incidence Rates of Autoimmune Diseases in European Healthcare Databases: A Contribution of the ADVANCE Project

Willame C, Dodd C, van der Aa L, Picelli G, Emborg HD, Kahlert J, Gini R, Huerta C, Martín-Merino E, McGee C, de Lusignan S, Roberto G, Villa M, Weibel D, Titievsky L, Sturkenboom MCJM.
Drug Saf. 2021 Mar;44(3):383-395. doi: 10.1007/s40264-020-01031-1. Epub 2021 Jan 19.
PMID: 33462778

ACUTE RESPIRATORY TRACT INFECTIONS

Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population

Barbieri E, Cantarutti A, Cavagnis S, Cantarutti L, Baraldi E, Giaquinto C, Donà D.
NPJ Prim Care Respir Med. 2021 Mar 19;31(1):15. doi: 10.1038/s41533-021-00228-w.
PMID: 33741991

ACUTE RESPIRATORY TRACT INFECTIONS, Antibiotic treatment

Antibiotic Prescriptions for Children With Community-acquired Pneumonia: Findings From Italy

Costenaro P, Cantarutti A, Barbieri E, Scamarcia A, Oletto A, Sacerdoti P, Lundin R, Cantarutti L, Giaquinto C, Donà D.
Pediatr Infect Dis J. 2021 Feb 1;40(2):130-136. doi: 10.1097/INF.0000000000002934.
PMID: 33055500

Vaccination

Advance system testing: Vaccine benefit studies using multi-country electronic health data – The example of pertussis vaccination

Tin Tin Htar M, de Ridder M, Braeye T, Correa A, McGee C, de Lusignan S, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Tramontan L, Danieli G, Picelli G, van der Maas N, Berencsi K, Arnheim-Dahlström L, Heininger U, Emborg HD, Weibel D, Bollaerts K, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B31-B37. doi: 10.1016/j.vaccine.2019.08.078. Epub 2019 Oct 31.
PMID: 31677949

Other

ADVANCE system testing: Can safety studies be conducted using electronic healthcare data? An example using pertussis vaccination

Weibel D, Dodd C, Mahaux O, Haguinet F, De Smedt T, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Martín-Merino E, Huerta-Alvarez C, Berencsi K, Emborg HD, Bollaerts K, Bauchau V, Titievsky L, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B38-B46. doi: 10.1016/j.vaccine.2019.06.040. Epub 2019 Oct 31.
PMID: 31677946

Other

ADVANCE system testing: Benefit-risk analysis of a marketed vaccine using multi-criteria decision analysis and individual-level state transition modelling

Bollaerts K, Ledent E, de Smedt T, Weibel D, Emborg HD, Danieli G, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Picelli G, Tramontan L, Sturkenboom M, Bauchau V.
Vaccine. 2020 Dec 22;38 Suppl 2:B65-B75. doi: 10.1016/j.vaccine.2019.09.034. Epub 2019 Oct 31.
PMID: 31677947

Other

Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project

Gini R, Dodd CN, Bollaerts K, Bartolini C, Roberto G, Huerta-Alvarez C, Martín-Merino E, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Becker BFH, Switzer C, Gandhi-Banga S, Bauwens J, van der Maas NAT, Spiteri G, Sdona E, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B56-B64. doi: 10.1016/j.vaccine.2019.07.045. Epub 2019 Oct 31.
PMID: 31677950

Vaccination

ADVANCE system testing: Can coverage of pertussis vaccination be estimated in European countries using electronic healthcare databases: An example

Emborg HD, Kahlert J, Braeye T, Bauwens J, Bollaerts K, Danieli G, Duarte-Salles T, Glismann S, Huerta-Alvarez C, de Lusignan S, Martín-Merino E, McGee C, Correa A, Tramontan L, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B22-B30. doi: 10.1016/j.vaccine.2019.07.039. Epub 2019 Oct 31.
PMID: 31677953

Vaccination

ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations

Sturkenboom M, Braeye T, van der Aa L, Danieli G, Dodd C, Duarte-Salles T, Emborg HD, Gheorghe M, Kahlert J, Gini R, Huerta-Alvarez C, Martín-Merino E, McGee C, de Lusignan S, Picelli G, Roberto G, Tramontan L, Villa M, Weibel D, Titievsky L.
Vaccine. 2020 Dec 22;38 Suppl 2:B8-B21. doi: 10.1016/j.vaccine.2020.01.100. Epub 2020 Feb 12.
PMID: 32061385

Vaccination

ADVANCE system testing: Estimating the incidence of adverse events following pertussis vaccination in healthcare databases with incomplete exposure data

Dodd C, de Ridder M, Weibel D, Mahaux O, Haguinet F, de Smedt T, de Lusignan S, McGee C, Duarte-Salles T, Emborg HD, Huerta-Alvarez C, Martín-Merino E, Picelli G, Berencsi K, Danieli G, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B47-B55. doi: 10.1016/j.vaccine.2020.03.050. Epub 2020 Apr 9.
PMID: 32280043

Prevention

Preventing recurrent acute otitis media with Streptococcus salivarius 24SMB and Streptococcus oralis 89a five months intermittent treatment: An observational prospective cohort study

Cantarutti A, Rea F, Donà D, Cantarutti L, Passarella A, Scamarcia A, Lundin R, Damiani V, Giaquinto C, Corrao G.
Int J Pediatr Otorhinolaryngol. 2020 May;132:109921. doi: 10.1016/j.ijporl.2020.109921. Epub 2020 Feb 5.
PMID: 32062496

Vaccination

Age-specific vaccination coverage estimates for influenza, human papillomavirus and measles containing vaccines from seven population-based healthcare databases from four EU countries – The ADVANCE project

Braeye T, Emborg HD, Llorente-García A, Huerta C, Martín-Merino E, Duarte-Salles T, Danieli G, Tramontan L, Weibel D, McGee C, Villa M, Gini R, Lehtinen M, Titievsky L, Sturkenboom M.
Vaccine. 2020 Apr 3;38(16):3243-3254. doi: 10.1016/j.vaccine.2020.02.082. Epub 2020 Mar 12.
PMID: 32171573

ACUTE RESPIRATORY TRACT INFECTIONS, Antibiotic treatment

Antibiotic prescriptions in acute otitis media and pharyngitis in Italian pediatric outpatients

Barbieri E, Donà D, Cantarutti A, Lundin R, Scamarcia A, Corrao G, Cantarutti L, Giaquinto C.
Ital J Pediatr. 2019 Aug 17;45(1):103. doi: 10.1186/s13052-019-0696-9.
PMID: 31420054

Vaccination

Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy

Giaquinto C, Gabutti G, Baldo V, Villa M, Tramontan L, Raccanello N, Russo F, Poma C, Scamarcia A, Cantarutti L, Lundin R, Perinetti E, Cornen X, Thomas S, Ballandras C, Souverain A, Hartwig S.
BMC Infect Dis. 2018 Mar 5;18(1):103. doi: 10.1186/s12879-018-3017-9.
PMID: 29506477

Prevention

Galacto-Oligosaccharide/Polidextrose Enriched Formula Protects against Respiratory Infections in Infants at High Risk of Atopy: A Randomized Clinical Trial

Ranucci G, Buccigrossi V, Borgia E, Piacentini D, Visentin F, Cantarutti L, Baiardi P, Felisi M, Spagnuolo MI, Zanconato S, Baraldi E, Giaquinto C, Guarino A.
Nutrients. 2018 Mar 1;10(3):286. doi: 10.3390/nu10030286.
PMID: 29494489

ACUTE RESPIRATORY TRACT INFECTIONS

Incidence and clinical presentation of acute otitis media in children aged <6 years in European medical practices

Liese JG, Silfverdal SA, Giaquinto C, Carmona A, Larcombe JH, Garcia-Sicilia J, Fuat A, Garces-Sanchez M, Basanta ML, Hiraldo EM, Cantarutti L, Kroeniger W, Vollmar J, Holl K, Pirçon JY, Rosenlund MR.
Epidemiol Infect. 2014 Aug;142(8):1778-88. doi: 10.1017/S0950268813002744. Epub 2013 Dec 13.
PMID: 24330917

Other

Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and which study designs do we need to assess safety issues?

Valkhoff VE, Schade R, ‘t Jong GW, Romio S, Schuemie MJ, Arfe A, Garbe E, Herings R, Lucchi S, Picelli G, Schink T, Straatman H, Villa M, Kuipers EJ, Sturkenboom MC; Safety of Non-steroidal Anti-inflammatory Drugs (SOS) project.
BMC Pediatr. 2013 Nov 19;13:192. doi: 10.1186/1471-2431-13-192.
PMID: 24252465

Other

Replication of the OMOP experiment in Europe: evaluating methods for risk identification in electronic health record databases

Schuemie MJ, Gini R, Coloma PM, Straatman H, Herings RM, Pedersen L, Innocenti F, Mazzaglia G, Picelli G, van der Lei J, Sturkenboom MC.
Drug Saf. 2013 Oct;36 Suppl 1:S159-69. doi: 10.1007/s40264-013-0109-8.
PMID: 24166232

ACUTE RESPIRATORY TRACT INFECTIONS

Burden of acute otitis media in primary care pediatrics in Italy: a secondary data analysis from the Pedianet database

Marchisio P, Cantarutti L, Sturkenboom M, Girotto S, Picelli G, Dona D, Scamarcia A, Villa M, Giaquinto C; Pedianet.
BMC Pediatr. 2012 Nov 29;12:185. doi: 10.1186/1471-2431-12-185.
PMID: 23190626

Other

The prescribing of analgesics and non-steroidal anti-inflammatory drugs in paediatric primary care in the UK, Italy and the Netherlands

Neubert A, Verhamme K, Murray ML, Picelli G, Hsia Y, Sen FE, Giaquinto C, Ceci A, Sturkenboom M, Wong IC; TEDDY Network of Excellence.
Pharmacol Res. 2010 Sep;62(3):243-8. doi: 10.1016/j.phrs.2010.04.006. Epub 2010 May 6.
PMID: 20451614

Other

Comparison of antiepileptic drug prescribing in children in three European countries

Hsia Y, Neubert A, Sturkenboom MC, Murray ML, Verhamme KM, Sen F, Giaquinto C, Ceci A, Wong IC; TEDDY Network of Excellence.
Epilepsia. 2010 May;51(5):789-96. doi: 10.1111/j.1528-1167.2009.02331.x. Epub 2009 Oct 8.
PMID: 19817815

Other

In-label and off-label use of respiratory drugs in the Italian paediatric population

Baiardi P, Ceci A, Felisi M, Cantarutti L, Girotto S, Sturkenboom M, Baraldi E.
Acta Paediatr. 2010 Apr;99(4):544-9. doi: 10.1111/j.1651-2227.2009.01668.x. Epub 2010 Jan 27.
PMID: 20105140

Other

Drug use in children: cohort study in three European countries

Sturkenboom MC, Verhamme KM, Nicolosi A, Murray ML, Neubert A, Caudri D, Picelli G, Sen EF, Giaquinto C, Cantarutti L, Baiardi P, Felisi MG, Ceci A, Wong IC; TEDDY European Network of Excellence.
BMJ. 2008 Nov 24;337:a2245. doi: 10.1136/bmj.a2245.
PMID: 19029175

Other

[Epidemiology and outcomes of varicella in Italy: results of a prospective study of children (0-14 years old) followed up by pediatricians (Pedianet study)]

Giaquinto C, Sturkenboom M, Mannino S, Arpinelli F, Nicolosi A, Cantarutti L; Gruppo di studio sulla varicella in età pediatrica (Pedianet Varicella Study Group).
Ann Ig. 2002 Jul-Aug;14(4 Suppl 6):21-7.
PMID: 12389301 Italian. No abstract available.

Other

Active monitoring of adverse drug reactions in children. Italian Paediatric Pharmacosurveillance Multicenter Group

Menniti-Ippolito G, Raschetti R, Da Cas R, Giaquinto C, Cantarutti L.Lancet. 2000 May 6;355(9215):1613-4. doi: 10.1016/s0140-6736(00)02219-4.
PMID: 10821367