Prevention

Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population

Batzella E, Gutierrez de Rubalcava Doblas J, Porcu G, Bressan S, Barbieri E, Giaquinto C, Cantarutti A, Canova C.
Sci Rep. 2025 Jan 28;15(1):3525. doi: 10.1038/s41598-025-87997-3.
PMID: 39875635

Vaccination

A population database analysis to estimate the varicella vaccine effectiveness in children < 14 years in a high vaccination coverage area from 2004 to 2022

Barbieri E, Cocchio S, Furlan P, Scamarcia A, Cantarutti L, Dona’ D, Giaquinto C, Baldo V.
Vaccine. 2024 Dec 2;42(26):126387. doi: 10.1016/j.vaccine.2024.126387. Epub 2024 Sep 26.
PMID: 39332238

SARS-CoV-2

Incidence of severe and non-severe SARS-CoV-2 infections in children and adolescents: a population-based cohort study using six healthcare databases from Italy, Spain, and Norway

Durán CE, Riefolo F, Gini R, Barbieri E, Messina D, Garcia P, Martin M, Villalobos F, Stona L, Carreras JJ, Urchueguía A, Correcher-Martínez E, Zhao J, Lupattelli A, Nordeng H, Sturkenboom M.
Eur J Pediatr. 2024 Nov 13;184(1):6. doi: 10.1007/s00431-024-05864-1.
PMID: 39535547

Influenza – Influenza vaccination

Cost-Effectiveness of Influenza Vaccination in Healthy Children: A 10-Year Population-Based Study

Barbieri E, Wang Y, Cantarutti A, Scamarcia A, Cantarutti L, Corrao G, Torbica A, Giaquinto C.
Vaccines (Basel). 2024 Sep 28;12(10):1113. doi: 10.3390/vaccines12101113.
PMID: 39460280

Chronic inflammatory disease

Epidemiological analysis to identify predictors of X-linked hypophosphatemia (XLH) diagnosis in an Italian pediatric population: the EPIX project

Crisafulli S, Ingrasciotta Y, Vitturi G, Fontana A, L’Abbate L, Alessi Y, Ferraù F, Cantarutti L, Lazzerini D, Cannavò S, Trifirò G.
Endocrine. 2024 Aug;85(2):894-905. doi: 10.1007/s12020-024-03793-5. Epub 2024 Apr 9.
PMID: 38592637

SARS-CoV-2

Drug utilisation in children and adolescents before and after the start of the COVID-19 pandemic: Interrupted time-series analyses in three European countries

Pedersen E, Tripodi E, Aakjær M, Li H, Cantarutti A, Nyberg F, Andersen M, Lupattelli A, Nordeng H.Paediatr Perinat Epidemiol. 2024 Aug;38(6):450-460. doi: 10.1111/ppe.13046. Epub 2024 Feb 1.
PMID: 38299727

SARS-CoV-2

Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19

Di Chiara C, Barbieri E, Chen YX, Visonà E, Cavagnis S, Sturniolo G, Parca A, Liberati C, Cantarutti L, Lupattelli A, Le Prevost M, Corrao G, Giaquinto C, Donà D, Cantarutti A.
Acta Paediatr. 2023 Dec;112(12):2563-2571. doi: 10.1111/apa.16966. Epub 2023 Sep 9.
PMID: 37688774

Influenza – Influenza vaccination

Epidemiology and Burden of Influenza in Children 0-14 Years Over Ten Consecutive Seasons in Italy

Barbieri E, Porcu G, Donà D, Cavagnis S, Cantarutti L, Scamarcia A, McGovern I, Haag M, Giaquinto C, Cantarutti A.
Pediatr Infect Dis J. 2023 Dec 1;42(12):e440-e446. doi: 10.1097/INF.0000000000004090. Epub 2023 Sep 7.
PMID: 37725811

Chronic inflammatory disease

Epidemiology of pediatric psoriasis: a population-based study using two Italian data sources

Lapi F, Cassano N, Barbieri E, Marconi E, Vena GA, Giaquinto C, Cricelli C.
Curr Med Res Opin. 2023 Sep;39(9):1257-1262. doi: 10.1080/03007995.2023.2243216. Epub 2023 Aug 10.
PMID: 37526047 Review.

SARS-CoV-2

The Association Between Pediatric COVID-19 Vaccination and Socioeconomic Position: Nested Case-Control Study From the Pedianet Veneto Cohort

Batzella E, Cantarutti A, Caranci N, Giaquinto C, Barbiellini Amidei C, Canova C. JMIR Public Health Surveill.
2023 Feb 1;9:e44234. doi: 10.2196/44234.
PMID: 36645419

Machine learning

A Deep Learning Approach to Estimate the Incidence of Infectious Disease Cases for Routinely Collected Ambulatory Records: The Example of Varicella-Zoster

Lanera C, Baldi I, Francavilla A, Barbieri E, Tramontan L, Scamarcia A, Cantarutti L, Giaquinto C, Gregori D.
Int J Environ Res Public Health. 2022 May 13;19(10):5959. doi: 10.3390/ijerph19105959.
PMID: 35627495

Influenza – Influenza vaccination

Influenza Vaccination Effectiveness in Paediatric ‘Healthy’ Patients: A Population-Based Study in Italy

Cantarutti A, Barbieri E, Didonè F, Scamarcia A, Giaquinto C, Corrao G.
Vaccines (Basel). 2022 Apr 10;10(4):582. doi: 10.3390/vaccines10040582.
PMID: 35455331

Prevention

Use of the Bacterial Lysate OM-85 in the Paediatric Population in Italy: A Retrospective Cohort Study

Cantarutti A, Barbieri E, Scamarcia A, Cantarutti L, Canova C, Giaquinto C.
Int J Environ Res Public Health. 2021 Jun 26;18(13):6871. doi: 10.3390/ijerph18136871.
PMID: 34206831

Other

Incidence Rates of Autoimmune Diseases in European Healthcare Databases: A Contribution of the ADVANCE Project

Willame C, Dodd C, van der Aa L, Picelli G, Emborg HD, Kahlert J, Gini R, Huerta C, Martín-Merino E, McGee C, de Lusignan S, Roberto G, Villa M, Weibel D, Titievsky L, Sturkenboom MCJM.
Drug Saf. 2021 Mar;44(3):383-395. doi: 10.1007/s40264-020-01031-1. Epub 2021 Jan 19.
PMID: 33462778

Vaccination

Advance system testing: Vaccine benefit studies using multi-country electronic health data – The example of pertussis vaccination

Tin Tin Htar M, de Ridder M, Braeye T, Correa A, McGee C, de Lusignan S, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Tramontan L, Danieli G, Picelli G, van der Maas N, Berencsi K, Arnheim-Dahlström L, Heininger U, Emborg HD, Weibel D, Bollaerts K, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B31-B37. doi: 10.1016/j.vaccine.2019.08.078. Epub 2019 Oct 31.
PMID: 31677949

Other

ADVANCE system testing: Can safety studies be conducted using electronic healthcare data? An example using pertussis vaccination

Weibel D, Dodd C, Mahaux O, Haguinet F, De Smedt T, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Martín-Merino E, Huerta-Alvarez C, Berencsi K, Emborg HD, Bollaerts K, Bauchau V, Titievsky L, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B38-B46. doi: 10.1016/j.vaccine.2019.06.040. Epub 2019 Oct 31.
PMID: 31677946

Other

ADVANCE system testing: Benefit-risk analysis of a marketed vaccine using multi-criteria decision analysis and individual-level state transition modelling

Bollaerts K, Ledent E, de Smedt T, Weibel D, Emborg HD, Danieli G, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Picelli G, Tramontan L, Sturkenboom M, Bauchau V.
Vaccine. 2020 Dec 22;38 Suppl 2:B65-B75. doi: 10.1016/j.vaccine.2019.09.034. Epub 2019 Oct 31.
PMID: 31677947

Other

Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project

Gini R, Dodd CN, Bollaerts K, Bartolini C, Roberto G, Huerta-Alvarez C, Martín-Merino E, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Becker BFH, Switzer C, Gandhi-Banga S, Bauwens J, van der Maas NAT, Spiteri G, Sdona E, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B56-B64. doi: 10.1016/j.vaccine.2019.07.045. Epub 2019 Oct 31.
PMID: 31677950

Vaccination

ADVANCE system testing: Can coverage of pertussis vaccination be estimated in European countries using electronic healthcare databases: An example

Emborg HD, Kahlert J, Braeye T, Bauwens J, Bollaerts K, Danieli G, Duarte-Salles T, Glismann S, Huerta-Alvarez C, de Lusignan S, Martín-Merino E, McGee C, Correa A, Tramontan L, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B22-B30. doi: 10.1016/j.vaccine.2019.07.039. Epub 2019 Oct 31.
PMID: 31677953

Vaccination

ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations

Sturkenboom M, Braeye T, van der Aa L, Danieli G, Dodd C, Duarte-Salles T, Emborg HD, Gheorghe M, Kahlert J, Gini R, Huerta-Alvarez C, Martín-Merino E, McGee C, de Lusignan S, Picelli G, Roberto G, Tramontan L, Villa M, Weibel D, Titievsky L.
Vaccine. 2020 Dec 22;38 Suppl 2:B8-B21. doi: 10.1016/j.vaccine.2020.01.100. Epub 2020 Feb 12.
PMID: 32061385

Vaccination

ADVANCE system testing: Estimating the incidence of adverse events following pertussis vaccination in healthcare databases with incomplete exposure data

Dodd C, de Ridder M, Weibel D, Mahaux O, Haguinet F, de Smedt T, de Lusignan S, McGee C, Duarte-Salles T, Emborg HD, Huerta-Alvarez C, Martín-Merino E, Picelli G, Berencsi K, Danieli G, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B47-B55. doi: 10.1016/j.vaccine.2020.03.050. Epub 2020 Apr 9.
PMID: 32280043

Chronic inflammatory disease

Incidence, risk factors and re-exacerbation rate of severe asthma exacerbations in a multinational, multidatabase pediatric cohort study

Engelkes M, Baan EJ, de Ridder MAJ, Svensson E, Prieto-Alhambra D, Lapi F, Giaquinto C, Picelli G, Boudiaf N, Albers F, Evitt LA, Cockle S, Bradford E, Van Dyke MK, Suruki R, Rijnbeek P, Sturkenboom MCJM, Janssens HM, Verhamme KMC.
Pediatr Allergy Immunol. 2020 Jul;31(5):496-505. doi: 10.1111/pai.13237. Epub 2020 Mar 20.
PMID: 32115766

Prevention

Preventing recurrent acute otitis media with Streptococcus salivarius 24SMB and Streptococcus oralis 89a five months intermittent treatment: An observational prospective cohort study

Cantarutti A, Rea F, Donà D, Cantarutti L, Passarella A, Scamarcia A, Lundin R, Damiani V, Giaquinto C, Corrao G.
Int J Pediatr Otorhinolaryngol. 2020 May;132:109921. doi: 10.1016/j.ijporl.2020.109921. Epub 2020 Feb 5.
PMID: 32062496

Machine learning

Use of Machine Learning Techniques for Case-Detection of Varicella Zoster Using Routinely Collected Textual Ambulatory Records: Pilot Observational Study

Lanera C, Berchialla P, Baldi I, Lorenzoni G, Tramontan L, Scamarcia A, Cantarutti L, Giaquinto C, Gregori D.
JMIR Med Inform. 2020 May 5;8(5):e14330. doi: 10.2196/14330.
PMID: 32369038

Chronic inflammatory disease

Multinational cohort study of mortality in patients with asthma and severe asthma

Engelkes M, de Ridder MA, Svensson E, Berencsi K, Prieto-Alhambra D, Lapi F, Giaquinto C, Picelli G, Boudiaf N, Albers FC, Cockle SM, Bradford ES, Suruki RY, Brusselle GG, Rijnbeek PR, Sturkenboom MC, Verhamme KM.
Respir Med. 2020 Apr-May;165:105919. doi: 10.1016/j.rmed.2020.105919. Epub 2020 Mar 2.
PMID: 32174450

Vaccination

Age-specific vaccination coverage estimates for influenza, human papillomavirus and measles containing vaccines from seven population-based healthcare databases from four EU countries – The ADVANCE project

Braeye T, Emborg HD, Llorente-García A, Huerta C, Martín-Merino E, Duarte-Salles T, Danieli G, Tramontan L, Weibel D, McGee C, Villa M, Gini R, Lehtinen M, Titievsky L, Sturkenboom M.
Vaccine. 2020 Apr 3;38(16):3243-3254. doi: 10.1016/j.vaccine.2020.02.082. Epub 2020 Mar 12.
PMID: 32171573

Vaccination

Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy

Giaquinto C, Gabutti G, Baldo V, Villa M, Tramontan L, Raccanello N, Russo F, Poma C, Scamarcia A, Cantarutti L, Lundin R, Perinetti E, Cornen X, Thomas S, Ballandras C, Souverain A, Hartwig S.
BMC Infect Dis. 2018 Mar 5;18(1):103. doi: 10.1186/s12879-018-3017-9.
PMID: 29506477

Prevention

Galacto-Oligosaccharide/Polidextrose Enriched Formula Protects against Respiratory Infections in Infants at High Risk of Atopy: A Randomized Clinical Trial

Ranucci G, Buccigrossi V, Borgia E, Piacentini D, Visentin F, Cantarutti L, Baiardi P, Felisi M, Spagnuolo MI, Zanconato S, Baraldi E, Giaquinto C, Guarino A.
Nutrients. 2018 Mar 1;10(3):286. doi: 10.3390/nu10030286.
PMID: 29494489

Other

Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and which study designs do we need to assess safety issues?

Valkhoff VE, Schade R, ‘t Jong GW, Romio S, Schuemie MJ, Arfe A, Garbe E, Herings R, Lucchi S, Picelli G, Schink T, Straatman H, Villa M, Kuipers EJ, Sturkenboom MC; Safety of Non-steroidal Anti-inflammatory Drugs (SOS) project.
BMC Pediatr. 2013 Nov 19;13:192. doi: 10.1186/1471-2431-13-192.
PMID: 24252465

Other

Replication of the OMOP experiment in Europe: evaluating methods for risk identification in electronic health record databases

Schuemie MJ, Gini R, Coloma PM, Straatman H, Herings RM, Pedersen L, Innocenti F, Mazzaglia G, Picelli G, van der Lei J, Sturkenboom MC.
Drug Saf. 2013 Oct;36 Suppl 1:S159-69. doi: 10.1007/s40264-013-0109-8.
PMID: 24166232

Other

The prescribing of analgesics and non-steroidal anti-inflammatory drugs in paediatric primary care in the UK, Italy and the Netherlands

Neubert A, Verhamme K, Murray ML, Picelli G, Hsia Y, Sen FE, Giaquinto C, Ceci A, Sturkenboom M, Wong IC; TEDDY Network of Excellence.
Pharmacol Res. 2010 Sep;62(3):243-8. doi: 10.1016/j.phrs.2010.04.006. Epub 2010 May 6.
PMID: 20451614

Other

Comparison of antiepileptic drug prescribing in children in three European countries

Hsia Y, Neubert A, Sturkenboom MC, Murray ML, Verhamme KM, Sen F, Giaquinto C, Ceci A, Wong IC; TEDDY Network of Excellence.
Epilepsia. 2010 May;51(5):789-96. doi: 10.1111/j.1528-1167.2009.02331.x. Epub 2009 Oct 8.
PMID: 19817815

Other

In-label and off-label use of respiratory drugs in the Italian paediatric population

Baiardi P, Ceci A, Felisi M, Cantarutti L, Girotto S, Sturkenboom M, Baraldi E.
Acta Paediatr. 2010 Apr;99(4):544-9. doi: 10.1111/j.1651-2227.2009.01668.x. Epub 2010 Jan 27.
PMID: 20105140

Other

Drug use in children: cohort study in three European countries

Sturkenboom MC, Verhamme KM, Nicolosi A, Murray ML, Neubert A, Caudri D, Picelli G, Sen EF, Giaquinto C, Cantarutti L, Baiardi P, Felisi MG, Ceci A, Wong IC; TEDDY European Network of Excellence.
BMJ. 2008 Nov 24;337:a2245. doi: 10.1136/bmj.a2245.
PMID: 19029175

Chronic inflammatory disease

Asthma prevalence and drug prescription in asthmatic children

Barbato A, Panizzolo C, Biserna L, Cantarutti L, Giaquinto C, Frati F, Marcucci F, Monciotti C, Testi R, di Blasi P, Sturkenboom MC; Pedianet Family Pediatricians Asthma Study Group (F-PASG).
Eur Ann Allergy Clin Immunol. 2003 Feb;35(2):47-51.
PMID: 12674038

Other

[Epidemiology and outcomes of varicella in Italy: results of a prospective study of children (0-14 years old) followed up by pediatricians (Pedianet study)]

Giaquinto C, Sturkenboom M, Mannino S, Arpinelli F, Nicolosi A, Cantarutti L; Gruppo di studio sulla varicella in età pediatrica (Pedianet Varicella Study Group).
Ann Ig. 2002 Jul-Aug;14(4 Suppl 6):21-7.
PMID: 12389301 Italian. No abstract available.

Other

Active monitoring of adverse drug reactions in children. Italian Paediatric Pharmacosurveillance Multicenter Group

Menniti-Ippolito G, Raschetti R, Da Cas R, Giaquinto C, Cantarutti L.Lancet. 2000 May 6;355(9215):1613-4. doi: 10.1016/s0140-6736(00)02219-4.
PMID: 10821367