Prevention

Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population

Batzella E, Gutierrez de Rubalcava Doblas J, Porcu G, Bressan S, Barbieri E, Giaquinto C, Cantarutti A, Canova C.
Sci Rep. 2025 Jan 28;15(1):3525. doi: 10.1038/s41598-025-87997-3.
PMID: 39875635

Vaccination

A population database analysis to estimate the varicella vaccine effectiveness in children < 14 years in a high vaccination coverage area from 2004 to 2022

Barbieri E, Cocchio S, Furlan P, Scamarcia A, Cantarutti L, Dona’ D, Giaquinto C, Baldo V.
Vaccine. 2024 Dec 2;42(26):126387. doi: 10.1016/j.vaccine.2024.126387. Epub 2024 Sep 26.
PMID: 39332238

Antibiotic treatment, Dermatological disorders

Retrospective Analysis of the Real-World Use of Topical Antimicrobials in the Paediatric Population with Impetigo in Italy: Focus on the Role of Ozenoxacin 1% Cream

Barbieri E, Cavagnis S, Boracchini R, Scamarcia A, Testa A, Ciarniello MG, Martinelli B, Cantarutti L, Giaquinto C, Cantarutti A. Children (Basel). 2023 Mar 13;10(3):547. doi: 10.3390/children10030547.
PMID: 36980105

Antibiotic treatment, Dermatological disorders

Early-life exposure to antibiotics and subsequent development of atopic dermatitis

Cantarutti A, Amidei CB, Bonaugurio AS, Rescigno P, Canova C.
Expert Rev Clin Pharmacol. 2022 Jun;15(6):779-785. doi: 10.1080/17512433.2022.2092471. Epub 2022 Jun 21.
PMID: 35723891

Dermatological disorders

Non-bullous Impetigo: Incidence, Prevalence, and Treatment in the Pediatric Primary Care Setting in Italy

Barbieri E, Porcu G, Dona’ D, Falsetto N, Biava M, Scamarcia A, Cantarutti L, Cantarutti A, Giaquinto C.
Front Pediatr. 2022 Mar 31;10:753694. doi: 10.3389/fped.2022.753694. eCollection 2022.
PMID: 35433549

Gastrointestinal diseases

Association of Treated and Untreated Gastroesophageal Reflux Disease in the First Year of Life with the Subsequent Development of Asthma

Cantarutti A, Barbiellini Amidei C, Valsecchi C, Scamarcia A, Corrao G, Gregori D, Giaquinto C, Ludvigsson JF, Canova C.
Int J Environ Res Public Health. 2021 Sep 13;18(18):9633. doi: 10.3390/ijerph18189633.
PMID: 34574556

Prevention

Use of the Bacterial Lysate OM-85 in the Paediatric Population in Italy: A Retrospective Cohort Study

Cantarutti A, Barbieri E, Scamarcia A, Cantarutti L, Canova C, Giaquinto C.
Int J Environ Res Public Health. 2021 Jun 26;18(13):6871. doi: 10.3390/ijerph18136871.
PMID: 34206831

Other

Incidence Rates of Autoimmune Diseases in European Healthcare Databases: A Contribution of the ADVANCE Project

Willame C, Dodd C, van der Aa L, Picelli G, Emborg HD, Kahlert J, Gini R, Huerta C, Martín-Merino E, McGee C, de Lusignan S, Roberto G, Villa M, Weibel D, Titievsky L, Sturkenboom MCJM.
Drug Saf. 2021 Mar;44(3):383-395. doi: 10.1007/s40264-020-01031-1. Epub 2021 Jan 19.
PMID: 33462778

Vaccination

Advance system testing: Vaccine benefit studies using multi-country electronic health data – The example of pertussis vaccination

Tin Tin Htar M, de Ridder M, Braeye T, Correa A, McGee C, de Lusignan S, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Tramontan L, Danieli G, Picelli G, van der Maas N, Berencsi K, Arnheim-Dahlström L, Heininger U, Emborg HD, Weibel D, Bollaerts K, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B31-B37. doi: 10.1016/j.vaccine.2019.08.078. Epub 2019 Oct 31.
PMID: 31677949

Other

ADVANCE system testing: Can safety studies be conducted using electronic healthcare data? An example using pertussis vaccination

Weibel D, Dodd C, Mahaux O, Haguinet F, De Smedt T, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Martín-Merino E, Huerta-Alvarez C, Berencsi K, Emborg HD, Bollaerts K, Bauchau V, Titievsky L, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B38-B46. doi: 10.1016/j.vaccine.2019.06.040. Epub 2019 Oct 31.
PMID: 31677946

Other

ADVANCE system testing: Benefit-risk analysis of a marketed vaccine using multi-criteria decision analysis and individual-level state transition modelling

Bollaerts K, Ledent E, de Smedt T, Weibel D, Emborg HD, Danieli G, Duarte-Salles T, Huerta-Alvarez C, Martín-Merino E, Picelli G, Tramontan L, Sturkenboom M, Bauchau V.
Vaccine. 2020 Dec 22;38 Suppl 2:B65-B75. doi: 10.1016/j.vaccine.2019.09.034. Epub 2019 Oct 31.
PMID: 31677947

Other

Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project

Gini R, Dodd CN, Bollaerts K, Bartolini C, Roberto G, Huerta-Alvarez C, Martín-Merino E, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Becker BFH, Switzer C, Gandhi-Banga S, Bauwens J, van der Maas NAT, Spiteri G, Sdona E, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B56-B64. doi: 10.1016/j.vaccine.2019.07.045. Epub 2019 Oct 31.
PMID: 31677950

Vaccination

ADVANCE system testing: Can coverage of pertussis vaccination be estimated in European countries using electronic healthcare databases: An example

Emborg HD, Kahlert J, Braeye T, Bauwens J, Bollaerts K, Danieli G, Duarte-Salles T, Glismann S, Huerta-Alvarez C, de Lusignan S, Martín-Merino E, McGee C, Correa A, Tramontan L, Weibel D, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B22-B30. doi: 10.1016/j.vaccine.2019.07.039. Epub 2019 Oct 31.
PMID: 31677953

Vaccination

ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations

Sturkenboom M, Braeye T, van der Aa L, Danieli G, Dodd C, Duarte-Salles T, Emborg HD, Gheorghe M, Kahlert J, Gini R, Huerta-Alvarez C, Martín-Merino E, McGee C, de Lusignan S, Picelli G, Roberto G, Tramontan L, Villa M, Weibel D, Titievsky L.
Vaccine. 2020 Dec 22;38 Suppl 2:B8-B21. doi: 10.1016/j.vaccine.2020.01.100. Epub 2020 Feb 12.
PMID: 32061385

Vaccination

ADVANCE system testing: Estimating the incidence of adverse events following pertussis vaccination in healthcare databases with incomplete exposure data

Dodd C, de Ridder M, Weibel D, Mahaux O, Haguinet F, de Smedt T, de Lusignan S, McGee C, Duarte-Salles T, Emborg HD, Huerta-Alvarez C, Martín-Merino E, Picelli G, Berencsi K, Danieli G, Sturkenboom M.
Vaccine. 2020 Dec 22;38 Suppl 2:B47-B55. doi: 10.1016/j.vaccine.2020.03.050. Epub 2020 Apr 9.
PMID: 32280043

Prevention

Preventing recurrent acute otitis media with Streptococcus salivarius 24SMB and Streptococcus oralis 89a five months intermittent treatment: An observational prospective cohort study

Cantarutti A, Rea F, Donà D, Cantarutti L, Passarella A, Scamarcia A, Lundin R, Damiani V, Giaquinto C, Corrao G.
Int J Pediatr Otorhinolaryngol. 2020 May;132:109921. doi: 10.1016/j.ijporl.2020.109921. Epub 2020 Feb 5.
PMID: 32062496

Vaccination

Age-specific vaccination coverage estimates for influenza, human papillomavirus and measles containing vaccines from seven population-based healthcare databases from four EU countries – The ADVANCE project

Braeye T, Emborg HD, Llorente-García A, Huerta C, Martín-Merino E, Duarte-Salles T, Danieli G, Tramontan L, Weibel D, McGee C, Villa M, Gini R, Lehtinen M, Titievsky L, Sturkenboom M.
Vaccine. 2020 Apr 3;38(16):3243-3254. doi: 10.1016/j.vaccine.2020.02.082. Epub 2020 Mar 12.
PMID: 32171573

Vaccination

Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy

Giaquinto C, Gabutti G, Baldo V, Villa M, Tramontan L, Raccanello N, Russo F, Poma C, Scamarcia A, Cantarutti L, Lundin R, Perinetti E, Cornen X, Thomas S, Ballandras C, Souverain A, Hartwig S.
BMC Infect Dis. 2018 Mar 5;18(1):103. doi: 10.1186/s12879-018-3017-9.
PMID: 29506477

Prevention

Galacto-Oligosaccharide/Polidextrose Enriched Formula Protects against Respiratory Infections in Infants at High Risk of Atopy: A Randomized Clinical Trial

Ranucci G, Buccigrossi V, Borgia E, Piacentini D, Visentin F, Cantarutti L, Baiardi P, Felisi M, Spagnuolo MI, Zanconato S, Baraldi E, Giaquinto C, Guarino A.
Nutrients. 2018 Mar 1;10(3):286. doi: 10.3390/nu10030286.
PMID: 29494489

Gastrointestinal diseases

Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases

Ferrajolo C, Verhamme KM, Trifirò G, ‘t Jong GW, Picelli G, Giaquinto C, Mazzaglia G, Stricker BH, Rossi F, Capuano A, Sturkenboom MC.
Drug Saf. 2017 Apr;40(4):305-315. doi: 10.1007/s40264-016-0493-y.
PMID: 28025733

Gastrointestinal diseases

Community-Acquired Rotavirus Gastroenteritis Compared with Adenovirus and Norovirus Gastroenteritis in Italian Children: A Pedianet Study

Donà D, Mozzo E, Scamarcia A, Picelli G, Villa M, Cantarutti L, Giaquinto C.
Int J Pediatr. 2016;2016:5236243. doi: 10.1155/2016/5236243. Epub 2016 Jan 14.
PMID: 26884770

Dermatological disorders

Epidemiology of Frequently Occurring Skin Diseases in Italian Children from 2006 to 2012: A Retrospective, Population-Based Study

Cantarutti A, Donà D, Visentin F, Borgia E, Scamarcia A, Cantarutti L, Peruzzi E, Egan CG, Villa M, Giaquinto C; Pedianet.
Pediatr Dermatol. 2015 Sep-Oct;32(5):668-78. doi: 10.1111/pde.12568. Epub 2015 Apr 16.
PMID: 25879514

Gastrointestinal diseases

Risk of upper gastrointestinal bleeding from different drug combinations

Masclee GM, Valkhoff VE, Coloma PM, de Ridder M, Romio S, Schuemie MJ, Herings R, Gini R, Mazzaglia G, Picelli G, Scotti L, Pedersen L, Kuipers EJ, van der Lei J, Sturkenboom MC.
Gastroenterology. 2014 Oct;147(4):784-792.e9; quiz e13-4. doi: 10.1053/j.gastro.2014.06.007. Epub 2014 Jun 14.
PMID: 24937265

Other

Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and which study designs do we need to assess safety issues?

Valkhoff VE, Schade R, ‘t Jong GW, Romio S, Schuemie MJ, Arfe A, Garbe E, Herings R, Lucchi S, Picelli G, Schink T, Straatman H, Villa M, Kuipers EJ, Sturkenboom MC; Safety of Non-steroidal Anti-inflammatory Drugs (SOS) project.
BMC Pediatr. 2013 Nov 19;13:192. doi: 10.1186/1471-2431-13-192.
PMID: 24252465

Other

Replication of the OMOP experiment in Europe: evaluating methods for risk identification in electronic health record databases

Schuemie MJ, Gini R, Coloma PM, Straatman H, Herings RM, Pedersen L, Innocenti F, Mazzaglia G, Picelli G, van der Lei J, Sturkenboom MC.
Drug Saf. 2013 Oct;36 Suppl 1:S159-69. doi: 10.1007/s40264-013-0109-8.
PMID: 24166232

Gastrointestinal diseases

Idiopathic acute liver injury in paediatric outpatients: incidence and signal detection in two European countries

Ferrajolo C, Verhamme KM, Trifirò G, ‘t Jong GW, Giaquinto C, Picelli G, Oteri A, de Bie S, Valkhoff VE, Schuemie MJ, Mazzaglia G, Cricelli C, Rossi F, Capuano A, Sturkenboom MC.
Drug Saf. 2013 Oct;36(10):1007-16. doi: 10.1007/s40264-013-0045-7.
PMID: 23591830

Other

The prescribing of analgesics and non-steroidal anti-inflammatory drugs in paediatric primary care in the UK, Italy and the Netherlands

Neubert A, Verhamme K, Murray ML, Picelli G, Hsia Y, Sen FE, Giaquinto C, Ceci A, Sturkenboom M, Wong IC; TEDDY Network of Excellence.
Pharmacol Res. 2010 Sep;62(3):243-8. doi: 10.1016/j.phrs.2010.04.006. Epub 2010 May 6.
PMID: 20451614

Other

Comparison of antiepileptic drug prescribing in children in three European countries

Hsia Y, Neubert A, Sturkenboom MC, Murray ML, Verhamme KM, Sen F, Giaquinto C, Ceci A, Wong IC; TEDDY Network of Excellence.
Epilepsia. 2010 May;51(5):789-96. doi: 10.1111/j.1528-1167.2009.02331.x. Epub 2009 Oct 8.
PMID: 19817815

Other

In-label and off-label use of respiratory drugs in the Italian paediatric population

Baiardi P, Ceci A, Felisi M, Cantarutti L, Girotto S, Sturkenboom M, Baraldi E.
Acta Paediatr. 2010 Apr;99(4):544-9. doi: 10.1111/j.1651-2227.2009.01668.x. Epub 2010 Jan 27.
PMID: 20105140

Other

Drug use in children: cohort study in three European countries

Sturkenboom MC, Verhamme KM, Nicolosi A, Murray ML, Neubert A, Caudri D, Picelli G, Sen EF, Giaquinto C, Cantarutti L, Baiardi P, Felisi MG, Ceci A, Wong IC; TEDDY European Network of Excellence.
BMJ. 2008 Nov 24;337:a2245. doi: 10.1136/bmj.a2245.
PMID: 19029175

Dermatological disorders

Incidence of mucocutaneous reactions in children treated with niflumic acid, other nonsteroidal antiinflammatory drugs, or nonopioid analgesics

Sturkenboom M, Nicolosi A, Cantarutti L, Mannino S, Picelli G, Scamarcia A, Giaquinto C; NSAIDs Paediatric Research Group.
Pediatrics. 2005 Jul;116(1):e26-33. doi: 10.1542/peds.2004-0040. Epub 2005 Jun 1.
PMID: 15930187

Other

[Epidemiology and outcomes of varicella in Italy: results of a prospective study of children (0-14 years old) followed up by pediatricians (Pedianet study)]

Giaquinto C, Sturkenboom M, Mannino S, Arpinelli F, Nicolosi A, Cantarutti L; Gruppo di studio sulla varicella in età pediatrica (Pedianet Varicella Study Group).
Ann Ig. 2002 Jul-Aug;14(4 Suppl 6):21-7.
PMID: 12389301 Italian. No abstract available.

Other

Active monitoring of adverse drug reactions in children. Italian Paediatric Pharmacosurveillance Multicenter Group

Menniti-Ippolito G, Raschetti R, Da Cas R, Giaquinto C, Cantarutti L.Lancet. 2000 May 6;355(9215):1613-4. doi: 10.1016/s0140-6736(00)02219-4.
PMID: 10821367